Renaissance Women's Group – Austin OBGYN

COLARIS testing

COLARIS® testing checks for an inherited disorder that puts women at higher risk for colorectal and endometrial cancer.

Our Austin ob/gyns keep our patients well informed about their health. COLARIS® testing provides an easy way for patients to determine if they have Lynch Syndrome. Lynch Syndrome, which is also known as hereditary nonpolyposis colorectal cancer (HNPCC), is a hereditary condition that puts people at an increased risk for developing colorectal cancer, as well as other related cancers affecting the liver, pancreas, stomach, small intestine, upper urinary tract, stomach, skin and brain. It also puts people at an increased risk for developing these cancers before age 50.

A mutation in the MLH1, MSH2, MSH6, PMS2 and EPCAM genes have all been linked with Lynch Syndrome, but mutations are most commonly found on the MLH1 and MSH2 genes. COLARIS® testing will identify these mutations and at-risk patients.

For women with Lynch Syndrome, there is an increased risk of developing endometrial (lining of the uterus) cancer, as well as ovarian cancer.

Who should have COLARIS ® testing?

Our Austin ob/gyns take an extensive family history, and part of that history involves finding out your family health history. We may recommend COLARIS ® testing if you have one or more first-degree relatives (parents, siblings or children) who have had colorectal cancer, or related cancers, such as endometrial, ovarian, stomach, etc.

Patients who have two or more second-degree relatives (grandparents, aunts, uncles, nieces, nephews, or half-siblings) who have had Lynch Syndrome related cancers may also consider having COLARIS ® testing. In addition, patients who have had colorectal cancer should discuss the benefits of COLARIS® testing with our Austin ob/gyns.

What are the benefits of COLARIS® testing?

Myriad’s MyRisk™ Hereditary Cancer panel is another testing option we recommend for patients. This 25-gene panel identifies elevated risk factors for breast, ovarian, gastric, colorectal, pancreatic, melanoma, endometrial and prostate cancer.

When COLARIS® testing results show that a patient has tested positive for Lynch Syndrome, our Austin ob/gyns will develop an individualized patient plan that helps them carefully monitor the patient for signs and symptoms of cancer. Finding cancer early helps us treat it much more effectively.

Our Austin ob/gyns also work with the patient to take preventive measures that may help avoid cancer altogether. For example, if a patient has completed her family, she may want to discuss preventive measures like removing the uterus and/or ovaries.

COLARIS® testing is also important for a patient’s family. Children of Lynch Syndrome patients have a 50% risk for the genetic mutation, so having this important information can help prevent and screen for cancer in other family members.

What is involved in COLARIS® testing?

COLARIS® testing is very simple for patients—it involves either a blood draw to obtain a blood sample or using a mouth rinse to obtain an oral sample. Test results may take up to 21 days.

COLARIS® testing helps our Austin ob/gyns provide our patients with complete information about their health, and that’s important to us. For more information about COLARIS ® testing, contact us.